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v. infusion of salvianolate (n=265) or placebo (n=271). Salvianolate administration exerted beneficial effects on coronary microcirculation. There was a trend of reduced myocardial infarct size in the salvianolate group compared to the placebo group (P=0.07, although no significant difference in left ventricular ejection fraction was found between the two groups. Salvianolate administration is associated with improved myocardial perfusion in patients with STEMI undergoing PCI. A larger study is required to assess the impact of this th