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How Does Medication For ADHD Work? increase the levels of norepinephrine and dopamine in your brain, which can improve concentration and impulse control. They are available in both immediate-release (short acting) and extended release tablets. They are taken every day in the morning. Nonstimulant medicines take longer to work but can also improve the ability to control impulses and attention. Atomoxetine, Viloxazine and guanfacine are antidepressants that raise levels of nore