https://www.selleckchem.com/pr....oducts/Calcitriol-(R
The fungal indole alkaloids are a unique class of complex molecules that have a characteristic bicyclo[2.2.2]diazaoctane ring and frequently contain a spiro - oxindole moiety. While various strains produce these compounds, an intriguing case involves the formation of individual antipodes by two unique species of fungi in the generation of the potent anticancer agents (+)- and (-)-notoamide A. NotI and NotI ' have been characterized as flavin-dependent monooxygenases that catalyze epoxidation and semi-pinacol rearrangement
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