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Finding the Best ADHD Medication For Adults Many adult ADHD treatment plans are based on medications. However, finding the right medication and dosage isn't always simple. Stimulants: These drugs are used to treat both hyperactivity and inattention. They work by increasing the levels of chemicals in the brain which transmit messages between nerve cells. They are taken multiple times a day and begin working in less than one hour. Stimulants Stimulants are the first medications that doctors prescribe to treat ADHD. These drugs work by increasing activity in specifi