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Increased phrase of Mcp-1 and TNFα (p less then 0.05) together with activation of this SAPK/JNK signaling path can advertise chronic inflammation in adipose tissue. Transcriptome community analysis revealed the over-representation of genes involved with insulin signaling (Irs1, Igf2, Ide), lipid metabolic process (Nr1d1, Lpin1, Lrpap1) and angiogenesis (Dusp10, Tp53inp1).This study aimed to investigate the result regarding the l-arginine (Arg) addition and different amounts of ZnO f