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More importantly, H2O2 as oxidant could oxidize PTB7-Th to obtain oxidation product of PTB7-Th (OPP) with carbonyl group and carboxyl group, and the electron cloud density in donor part of the OPP was higher than that of PTB7-Th, therefrom producing the stronger electron-donating property and higher photoelectrochemical (PEC) reaction efficiency. As a proof of concept, the proposed PTB7-Th/H2O2 system was successfully applied in the construction of a label-free PEC aptasensor for sensitive analysis of CRP, which performed a wide detectio