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Treating ADHD Without Medication Many people suffering from ADHD have found it beneficial to treat their symptoms with no medication. Combining psychotherapy, behavior modification and natural remedies is often the best solution. Methylphenidate boosts certain brain chemicals that regulate impulses and attention. There are also non-stimulants such as guanfacine or atomoxetine. Psychotherapy, exercise, and a healthy sleep routine can all be beneficial. Some people with ADHD suffer from coexisting disorders such as anxiety or depression that can affect