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The aim of this study was to determine the feasibility of hypofractionated schedules for metastatic bone/bone marrow lesions in children and to investigate dosimetric differences to the healthy surrounding tissues compared to conventional schedules. 27 paediatric patients (mean age, 7years) with 50 metastatic bone/bone marrow lesions (n=26 cranial, n=24 extra-cranial) from solid primary tumours (neuroblastoma and sarcoma) were included. The PTV was a 2mm expansion of the GTV. A prescription dose of 36 and 54Gy EQD2 was used for neuroblast