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52-fold. The best producer-when TAL1, ENO2, ARO1, ARO4 K229L , ARO7 G141S , and TAL were overexpressed, and PDC5 and ARO10 were deleted-increased p-coumaric acid production by 14.08-fold (from 1.4 to 19.71 mg L-1). Our study provided a valuable insight into the optimization of l-tyrosine metabolic pathway.We employ the Cloud Regime (CR) concept to identify large-scale tropical convective systems and investigate their characteristics in terms of organization and precipitation. The tropical CRs (TCRs) are derived from Moderate Resolution