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Right here we examined clock function in Arabidopsis thaliana mutants with flawed protected responses and discovered that improved infection susceptibility 4 (eds4) displays alterations in a number of circadian rhythms. Mapping by sequencing uncovered that EDS4 encodes the ortholog of NUCLEOPORIN 205, a core part of the inner ring of the nuclear pore complex (NPC). Consistent with the theory that the NPC specifically modulates clock function, we discovered a stronger enrichment in core ti