https://www.selleckchem.com/pr....oducts/dimethindene-
The allostatic model of addiction suggests that negative affect, such as depressive symptoms, mediates the effect of stress on outcomes among individuals with substance use disorders. However, few longitudinal treatment studies have demonstrated this effect. We analyzed data from a 12-week randomized trial of galantamine and/or computerized cognitive-behavioral therapy (CBT4CBT) for individuals (N = 12 with cocaine use disorder in methadone treatment for opioid use disorder. We evaluated baseline perceived stress as a pre