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This study aimed to evaluate the clinical significance of granulation tissue after endoscopic carbon dioxide laser surgery for glottic cancer. This was a retrospective review of 36 patients who underwent endoscopic carbon dioxide laser surgery for T and T glottic cancer. Post-operative, endoscopic examinations were rated by three blinded otolaryngologists for time to heal and presence of granulation. Patient and surgical factors were compared with time to heal and granulation. A total of 16 of 36 wounds (44 per cent) developed granulat