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adjacent to vessels or vessels within the lesion, TANB should be considered. The aim of this study was to investigate temperature and time variations during root-end resection. Sixty human premolars were selected. The root canals were enlarged up to ProTaper X3 rotary instrument. A thermocouple was placed into the root canal 1 mm behind the resection line. The teeth were randomly divided into six groups according to the apical resection method steel bur, tungsten carbide bur, Lindeman bur, diamond bur, laser and ultrasonic surgical piez