https://hspsignaling.com/index.....php/usefulness-asso
Although aging will probably be connected with DNA harm, the involvement of Klotho in safeguarding cells from DNA damage is still not clear. In this study, we examined DNA damage in personal kidney cells and mouse kidney muscle after ionizing radiation (IR). The depletion and overexpression of Klotho in real human renal cells reduced and increased the mobile survival prices after IR, respectively. The formation of γ-H2AX foci, representing DNA harm, was considerab