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08; 95% CI 1.02, 1.14, p=0.02) compared to carcinoma in situ]. CONCLUSIONS Cumulatively, our results suggest that some broad measures of environmental quality are associated with invasive breast cancer but that associations vary by environmental domain, cancer stage, subtype, and urbanicity. IMPACT Our findings suggest that components of land quality (e.g. pesticide applications and animal facilities) warrant additional investigation in relation to invasive breast cancer. Copyright ©2020, American Association for Cancer Research.Rhabdo