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While OA ended up being usually viewed as a prototypical 'wear and tear' disease, it is now more accurately regarded as a disease associated with the whole shared involving cartilage together with subchondral bone and synovium. As more has grown to become understood associated with the pathophysiology of OA, it's become more and more common for it to be described making use of a number of overlapping phenotypes. Customers with OA will probably experience multiple phenotypes during their conditio