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ADHD Medication - Ritalin Ritalin (methylphenidate) is effective at managing ADHD symptoms in adults. It can make people feel "up," alert, awake, and filled with a sense of clarity. ADHD medications affect two brain chemicals, norepinephrine and dopamine. The majority of ADHD medications, such as Ritalin and Concerta are stimulants. There are also nonstimulant medications. Methylphenidat