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Finally, we outline the current challenges and future opportunities. Particularly, this review highlights the contributions of the computational studies and their complementarity with experiments in accelerating the study progress of high-performance sodium-ion SEs for ASSBs.β-Galactosidase (β-gal), well known as a useful reporter enzyme, is a potent biomarker for various diseases such as colorectal and ovarian cancers. We have developed a highly stable red-emissive ratiometric fluorescent probe (CCGal1) for quantitatively monitoring t