https://www.selleckchem.com/pr....oducts/Rapamycin.htm
FFA demonstrated significant upregulation of Th1/IFN (e.g. IFN-, CXCL9/CXCL1, JAK-STAT pathway (STAT1, JAK3), and fibrosis-related products (vimentin, fibronectin; p less then 0.05 for all), with no concomitant downregulation of hair keratins and the T-regulatory marker, FOXP3, which were decreased in AA. The stem cell markers CD200 and K15 demonstrated significantly reduced expression only in FFA (p less then 0.05). CONCLUSION These data suggest that follicular damage and loss of stem cells in FFA may be mediated through immune att
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