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Conclusion This study summarizes latest evidence of RRT for patients with LALI and may provide guidance for clinical practice.Study registration number INPLASY202040082.Background Hyperlipidemia is a common disease characterized as blood lipid metabolism disorders, which is always companied with obesity. Hyperlipidemia is the leading cause of the cardiovascular disease (CVD) closely associated with mortality, and the risk can further elevate in the obese population. Additionally, it induces stroke and acute pancreatitis. Studies demonstrated that acupoint c