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3-54.8% from 2012-2013 to 2016-2018, though the secondary species did not change significantly after normalization by PM2.5. These results were validated by diagnostic ratios, which indicated an increasing contribution from the secondary formation including nighttime reactions. This novel method for NACs detection may provide valuable insights into the formation mechanisms of NACs in the atmosphere.Oncolytic virus is an effective therapeutic strategy for cancer treatment, which exploits natural or manipulated viruses to selectively targ