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Occasion Sequence Analysis along with Predicting in the Hand-Foot-Mouth Condition Morbidity within The far east Using An Sophisticated Dramatical Removing Condition Space TBATS Style. Opioid substitution therapy (OST) with buprenorphine has been widely available in India since 2007, but the introduction of methadone occurred much later in 2012, and availability remains limited. Illicit injecting drug use is a long-standing public health problem in Manipur, a state in Northeast In