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AT/RT is an additional category of brain tumors that cause the clinically and electro-physiologically critical condition in a few days after the onset. Traumatic brain injury is a major health and socioeconomic problem and the first cause of young death worldwide. For this reason, the prevention of post-traumatic brain injury and the research of new methods for it are important today. In this study, we aimed to determine whether the use of antiepileptic drugs contributed to axonal healing after traumatic brain injury. Thirty-six Long-Evan