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Moreover, AGE-D modified the systemic glycosylation profile, as analyzed by lectin microarray, and increased Nε-carboxymethyllysine immunoreactivity and AGEs receptor levels in ileum and submandibular glands. These results had been associated to increased systemic levels of cytokines and reduced gut microbial composition and homeostasis. Significant correlations were recorded between changes in bacterial populace as well as in incretins and inflammatory markers amounts. Overall, our data indi