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Finding the Best ADHD Medication For Adults Many adult ADHD treatment plans are based on medications. But finding the right medication and dosage isn't always simple. Stimulants: These drugs are used to treat hyperactivity and inattention. They work by increasing levels of brain chemicals which transmit messages between nerve cells. They are usually taken multiple times per day and start working in less than an hour. Stimulants Most doctors begin with stimulants to treat ADHD. They work by incre