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A hydrodynamic/acoustic splitting method was used to examine the effect of supraglottal acoustics on fluid-structure interactions during human voice production in a two-dimensional computational model. The accuracy of the method in simulating compressible flows in typical human airway conditions was verified by comparing it to full compressible flow simulations. The method was coupled with a three-mass model of vocal fold lateral motion to simulate fluid-structure interactions during human voice production. By separating the acoustic pert