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n activities to support learning was low amongst children born preterm/LBW and/or with HIE. Programme interventions should encourage fathers to engage with their children given the benefits for children's development. Azathioprine and mercaptopurine are considered safe during pregnancy. However, the pharmacokinetic effects of pregnancy on thiopurine metabolism are undefined. To characterise thiopurine metabolism in pregnancy and measure infant metabolite levels and outcomes. Women with IBD who were taking a thiopurine and pregnant or try
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