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The decreases in anticorrelation were correlated with increased cognitive-perceptual deficits and disorganization factors of the schizotypal personality questionnaire, as well as reduced independence-performance of the social functioning scale for all participants together. This study, which links SPD pathology and social functioning deficits, is the first evidence of impaired large-scale intrinsic brain networks in SPD.Women are predicted to be disproportionately impacted by the COVID-19 pandemic due to increased carer responsibilities