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Moreover, transcript families such as ERF, WRKY, MYB and bZIP related gene accounted more in all treatment comparison. The RNA-sequence and qPCR results indicated that exogenous melatonin is closely associated with acid rain stress moderator and might be involved in alteration of differentially expressed genes (DEGs), biosynthesis of plant secondary metabolites and transcriptional factor encoding genes expression which might have potential application against environmental hazardous conditions.The occurrence and dissemination of antibiotic resistant genes (