https://www.selleckchem.com/pr....oducts/larotrectinib
Introduction Alterations of the epigenome may influence cancer initiation and progression. At the cellular level, histones are key regulators of chromatin accessibility and gene transcription; thus, inhibition of histone deacetylase enzymes (HDACs) constitutes an attractive target for therapy. In this study, we investigated the effects of the HDAC inhibitor Entinostat on oral squamous cell carcinoma (OSCC). Materials and methods We tested the effects of Entinostat on OSCC cell lines. Cell viability and growth were analyzed using M