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Starting from a general effective Lagrangian for lepton flavor violation (LFV) in quark-lepton transitions, we derive constraints on the effective coefficients from the high-mass tails of the dilepton processes p p → ℓ k ℓ l (with k ≠ l ). The current (projected) limits derived in this paper from LHC data with 36 fb - 1 ( 3 ab - 1 ) can be applied to generic new physics scenarios, including the ones with scalar, vector and tensor effective operators. For purely left-handed operators, we explicitly compare these LHC constraints with the