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3% on the membrane after filtration with 108 CFU mL-1 Escherichia coli and Staphylococcus aureus solution as feed, respectively. The coating layer and assembled nanocapsules endowed the membrane with improved lysozyme stability, anti-adhesion performance, and antibacterial activity. Stimuli-responsive lysozyme nanocapsule engineered microfiltration membranes show great potential for anti-biofouling in future practical application.Cancer is a dynamic disease with heterogenic molecular signatures and constantly evolves during the course of