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20 (95% CI 1.01-1.44; p=0.0422). The pooled incidence of all arterial events in patients with VTE was 11.3‰ per patient-year (95% CI 4.6-18., and was significantly higher than the 9.2‰ per patient-year (95% CI 2.0-16.4) obtained in controls (Incidence rate ratio, IRR 1.32; 95% CI 1.08-1.61; p=0.0103). The pooled frequency and pooled incidence of arterial events were also higher in patients with unprovoked VTE than in patients with provoked VTE (RR 2.12; 95% CI 1.38-3.24; p=0.0042; and IRR 2.26, 95% CI 1.45-3.49; p=0.0032). The frequency and incide