https://www.selleckchem.com/products/arn-509.html
Curcumin is the major bioactive polyphenolic ingredient of turmeric. Increasing evidence indicates that the health benefits of curcumin are mediated through its anti-inflammatory and antioxidant effects. Inflammasomes are essential components of inflammatory pathways that activate caspase-1 leading to pyroptosis and stimulate maturation and secretion of the proinflammatory cytokines, interleukin-1β (IL-1β) and interleukin-18 (IL-18) through nuclear factor kappa-B (NF-κ signaling. The current review outlines the mechanisms of curcumin
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