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The neuroendocrine-stress axis of nonmammalian species is evolutionarily conserved, which makes them useful to serve as important model systems for elucidating the function of the vertebrate stress response. The involvement of hypothalamo-pituitary-adrenal (HPA) axis hormones in regulation of stress and reproduction is well described in different vertebrates. However, the stress response is a complex process, which appears to be controlled by a number of neurochemicals in association with hypothalamo-pituitary-interrenal (HPI) axis or