https://www.selleckchem.com/pr....oducts/Paclitaxel(Ta
Alpha -adrenergic (α -AR) and cannabinoid CB (CB -R) receptors exert their functions modulating multiple signaling pathways, including MEK-ERK (extracellular signal-regulated kinases) and FADD (Fas-associated protein with death domain) cascades. These molecules are relevant in finding biased agonists with fewer side effects, but the mechanisms involving their modulations by α -AR- and CB -R in vivo are unclear. This study investigated the roles of Gαi and Gαz proteins in mediating α -AR- and CB -R-induced alterations of MEK-ER
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