https://www.selleckchem.com/pr....oducts/pqr309-bimira
There was little difference in TOPMed-based imputation quality among the arrays with 700k variants. Individual-level imputation quality varied widely between and within the three US studies. Imputation quality also varied across genomic regions, producing regions where even common (MAF 5%) variants were consistently not well imputed across ancestries. The extent to which array genotyping and imputation can approximate WGS therefore depends on reference panel, genotype array, sample ancestry, and genomic location. Imp
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