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Adult male C57BL/6 mice were uni-nephrectomised and received deoxycorticosterone acetate and saline to drink (1K/DOCA/salt) for 21 times. Control mice were uni-nephrectomised but received water within the same time period. Sub-groups of 1K/DOCA/salt-injured mice (n = 5-8 per group) had been treated with either serelaxin (0.5 mg·kg 1K/DOCA/salt-injured mice created elevated BP and hypertension-induced renal harm, infection and fibrosis. BM-MSCs alone decreased the injury-induce