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In addition, sample volume was reduced from 11.0 ± 6.5 to 9.4 ± 5.1 ml (P 0.001) in aerobic bottles and from 10.1 ± 5.6 to 8.8 ± 4.8 ml (P 0.001) in anaerobic bottles. Education of medical personnel is a simple and effective way to reduce iatrogenic blood loss and possibly moderate the extent of phlebotomy-induced anemia. Education of medical personnel is a simple and effective way to reduce iatrogenic blood loss and possibly moderate the extent of phlebotomy-induced anemia. Macrophages adapt to microenvironments, and change met