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M. and noon. Within 2 weeks of discontinuing metformin, there were no further "attacks", and the chronic daytime fatigue and somnolence significantly improved. CONCLUSIONS This case report suggests that there is a risk of symptomatic hypoglycemia with therapeutic doses of metformin. Although advised to be taken with meals to avoid gastrointestinal upset, patients should also be educated to take metformin with meals to reduce the risk of metformin-associated hypoglycemia. Prospective study. The aim of this study was to prospectively asses
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