https://dubermatinibinhibitor.....com/autonomic-as-wel
METHODS TERT and TERC mutants observed in DKC or cDKC clients were transfected into Saos-2 or VA13+TERT (TERT-expressing VA13 cells) cells to measure telomerase activity. RESULTS Telomerase activity in cells expressing a mutant detected in cDKC patients had been significantly lower (P less then .0001) compared to cells revealing the wild-type genetics. In inclusion, some TERT mutations seen in cDKC (p.P632R, p.T726M) caused weaker (P = .0013) suppression of telomerase activi
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