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The decreased activity of acetylcholinesterase reinforces the neurotoxic action in groups exposed to PLA BioMPs. The current study has confirmed the initial hypothesis and is an insight about the toxicity of these biopolymers in D. rerio larvae, since it deepens the discussion about the environmental risk of these substances in freshwater ecosystems.Plastic particles cause toxic effects on marine organisms but whether food particles can affect the toxic effects of plastic particles on filter feeding animals remains unknown. To evaluate