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This electrochemical conversion reaction can be extended to other TMOs (i.e., NiOx/NF and CoOx/NF) for promoted electrocatalytic water splitting performances. This study provides an in-depth understanding on the nature of atomic and electronic structure evolution to promote the electrocatalytic activity.We present a theory which allows us to calculate the interaction potential between charge-regulated metal nanoparticles inside an acid-electrolyte solution. The approach is based on the recently introduced model of charge regulation which