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ADHD Medications - Stimulant Or Non Stimulant? Stimulant drugs are the most popular treatment for ADHD, and for many people, they work effectively. Some suffer from negative side effects or they do not work. Some doctors prescribe stimulants along with non-stimulant ADHD medications. These include medications that treat high blood pressure, such as clonidine and guanfacine hcl (Tenex). These are among the other medications that promote wakefulness. Benefits Stimulants are the fi