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Post-inflammatory hyperpigmentation (PIH), a common sequela of acute or chronic cutaneous inflammation, is an acquired pigmentary disorder. The main treatments for PIH, such as topical agents, photoprotection, and chemical peeling, demonstrated different efficacies with inconsistent outcomes. Here, we reported a case of nasal PIH treated using a 755-nm alexandrite picosecond laser. The patient (female, aged 36 years) presented with a brown macula on the left side of the nasal dorsum 2 years ago, received treatment, and was followed up i