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Together, the datasets provide an important resource to increase our understanding of the regulation of migration in macrophages and to develop therapies targeting disease-enhancing macrophages. © 2020. Published by The Company of Biologists Ltd.USP16 (also known as UBP-M) has emerged as a histone H2AK119 deubiquitylase (DU implicated in the regulation of chromatin-associated processes and cell cycle progression. Despite this, available evidence suggests that this DUB is also present in the cytoplasm. How the nucleo-cytoplasmic trans
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