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The miRNome profile of endometrial tissues during the implantation window can predict the pregnancy outcome. #link# These data are crucial for opening new perspectives to predict implantation failure and consequently, to increase ART success. To assess the efficacy and safety of a new surgical approach for uterine preservation among patients with placenta accreta spectrum in a low-resource setting. The present prospective cohort included 63 women diagnosed with placenta accreta spectrum undergoing cesarean deliveries who desired future