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The SBAC was lower for patients with at least one bone bridge than for patients without (p less then 0.05). Patients with lumbar vertebral ankylosis had a higher risk of presenting an SBAC≤145 HU (OR 4.95 (95% CI 1.1-17.4)). Conclusion The presence of a bone bridge and complete ankylosis of lumbar vertebra were associated with a higher risk of SBAC under the fracture threshold, suggesting structural deterioration of trabecular bone in ankylosed vertebrae in AS patients.Objective To investigate predictors of disease flare after methotrexate discontinuation i