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This study highlights differences in severity reports between women and men and adds to the growing body of literature, indicating that current sham methodologies might be inadequate to maintain blinding. Research into cognitive performance during a hangover has produced equivocal findings. This study investigated the reliability of inducing hangover symptoms and effects on cognitive performance (including applied tasks) under standardised conditions. Twenty-one participants (13 M; 24 ± 3 years) completed two identical trials, involving