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How Does Medication For ADHD Work? Many adults and kids discover that ADHD medication can help improve their ability to concentrate and control impulses. It also helps them organize themselves. Your doctor will collaborate with you and your child to determine the best medication for them. Stimulants are the first-line treatment for ADHD. They boost the levels of two brain chemicals called norepinephrine and dopamine. Stimulants Stimulant medications for ADHD are effective by increasing the levels of certain brain